The polls are open for the 2010 ENnie Awards so vote if you want to.
I threw my votes behind the sf titles on the ballot, like Eclipse Phase, Diaspora, Doctor Who, Shadowrun and Rogue Trader. I also gave Hero System 6th edition high marks. I don't play Hero anymore, but I think it's one of the most influential systems in the history of the hobby, plus Steve Long has put out some great stuff for it. What are you going to vote for?